Key Publications:

1. Injury and neurodevelopmental programs shape glioblastoma.

   Brooks, L.J., Hill C.S., Simpson-Ragdale H., Clements M.P., Parrinello, S.

   Trends in Neurosciences, 2022.

2. The white matter is a pro-differentiative niche for glioblastoma.

   Brooks, L.J., Clements M.P., Burden, J.J., Kocher, D., Richards, L., Castro Devesa S., Zakka, L., Woodberry M., Ellis, M., Jaunmuktane, Z., Brandner S., Morrison G., Pollard S.M., Dirks P.B., Marguerat S., Parrinello S.

   Nature Communications, 2021.   

3. Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin.

   Garcia-Diaz, C§., Pöysti, A§., Mereu, E§., Clements, M.P†., Brooks, L.J†., Galvez-Cancino, F., Castillo, S.P., Tang, W., Beattie, G., Courtot, L., Ruiz, S., Roncaroli, F., Yuan, Y., Marguerat, S., Quezada, S.A., Heyn, H and Parrinello, S.

   Cell Reports, 2023. 

4. Vascular regulation of glioma stem-like cells: a balancing act.

   Brooks, L.J., Parrinello S.

   Current Opinion in Neurobiology, 2017.  

All Publications:

1. Detecting glioblastoma tumour margin using MTE-NODDI.

   Karamched S.R., Gorup D., Tolomeo D., Brooks, L.J, Gong T., Sølvsten Jørgensen A.C., Scott c Clements M., Kalber T.L., Wells JA., Stuckey D.J., Thorne L., Shahrezaei V., Marguerat S., Zhang G.H., Parrinello S., Lythgoe M.F.

   Imaging Neuroscience, 2025. 

2. Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin.

   Garcia-Diaz, C§., Pöysti, A§., Mereu, E§., Clements, M.P†., Brooks, L.J†., Galvez-Cancino, F., Castillo, S.P., Tang, W., Beattie, G., Courtot, L., Ruiz, S., Roncaroli, F., Yuan, Y., Marguerat, S., Quezada, S.A., Heyn, H and Parrinello, S.

   Cell Reports, 2023. 

3. Injury and neurodevelopmental programs shape glioblastoma.

   Brooks, L.J., Hill C.S., Simpson-Ragdale H., Clements M.P., Parrinello, S.

   Trends in Neurosciences, 2022.

4. The white matter is a pro-differentiative niche for glioblastoma.

   Brooks, L.J., Clements M.P., Burden, J.J., Kocher, D., Richards, L., Castro Devesa S., Zakka, L., Woodberry M., Ellis, M., Jaunmuktane, Z., Brandner S., Morrison G., Pollard S.M., Dirks P.B., Marguerat S., Parrinello S.

   Nature Communications, 2021.   

5. Vascular regulation of glioma stem-like cells: a balancing act.

   Brooks, L.J., Parrinello S.

   Current Opinion in Neurobiology, 2017.  

6. Fermentable carbohydrates stimulate FFAR2-dependent PYY cell expansion to increase satiety.

   Brooks, L., Viardot A, Stolarczyk E, Howard J, Cani P, Everard A, Tsakmaki A, Sleeth M, Psichas A, Anastasovskaj J, Bell J, Bell-Anderson K, Mackay C, Ghatei M, Bloom S, Frost G, Bewick G.

   Molecular metabolism, 2017. 

7. The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via FFA2 in rodents.

   Psichas A, Sleeth M, Murphy K, Brooks, L., Bewick G, Hanyaloglu A, Ghatei M, Bloom S, and Frost G.

   International Journal of Obesity, 2014.  

8. Expression and function of GPR43 in islets of Langerhans.

   Dogan M, Brooks, L., Bowe JE, Bewick, GA, Frost, G, Jones, PM, Persaud, SJ.

   Diabetic Medicine, 2013.  

9. Selective Ablation of Peptide YY Cells in Adult Mice Reveals Their Role in Beta Cell Survival.

   Sam A.H., Gunner D.J., King A., Persaud S.J., Brooks, L., Hostomska K., Ford H.E,, Liu B., Ghatei M.A., Bloom S.R,, Bewick G.A.

   Gastroenterology, 2012. 

10. Different changes in cortical tumor necrosis factor-α-related pathways in schizophrenia and mood disorders.

    Dean B, Gibbons AS, Tawadros N, Brooks, L., Everall IP and Scarr E.

    Molecular Psychiatry 2013. 18: p. 767–773. 

11. AMPA receptor expression is increased post-mortem samples of the anterior cingulate from subjects with major depressive disorder.

    Gibbons A.S., Brooks, L., Scarr E., Dean B.

    Journal of Affective Disorders, 2012.  

12. The neurobiology of APOE in schizophrenia and mood disorders.

    Gibbons A.S., Udawela M., Jeon W.J., Seo M.S., Brooks L., Dean.

    Frontiers in Biosciences, 2011.